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Showing posts with label Rats. Show all posts
Showing posts with label Rats. Show all posts

Wednesday, November 17, 2010

Chicago Using GPS-Collared Coyotes to Control Rodents?

by Jaymi Heimbuch
from: http://www.treehugger.com/

coyote in chicago photo
Photo via video from WGN-TV

Most of the time when a city has a rodent problem, they call in human exterminators. But Chicago seems to be testing out something slightly more... natural. After spotting a coyote running down State Street in Chicago, residents became aware of a project the city is testing out that includes allowing GPS-fitted coyotes to run free in the city specifically for them to gobble up problematic pests like rats, mice and rabbits. However, Chicago isn't letting coyotes run all over in order to keep the rat populations down. Rather, there is a much cooler project underway. Video of the wily coyote after the jump.


According to Chicago Breaking News, "Brad Block, a supervisor for the Chicago Commission on Animal Care and Control, said the animal has the run of the Loop to help deal with rats and mice. He said no one has called today to complain.

'He's not a threat...He's not going to pick up your children,' Block said. 'His job is to deal with all of the nuisance problems, like mice, rats and rabbits.'

Block said he believes the coyote is one of those fitted with a GPS device to monitor its whereabouts. He said the coyote is pretty timid and stays away from people."

Gizmodo jumps to another conclusion, stating, "Chicago police said they hadn't heard anything about any coyotes--but now the Chicago Commission on Animal Care and Control is saying that it's probably a coyote that was let loose in purpose. To kill rats and stuff."

Rather than let loose on purpose -- which these urban coyotes are not -- the GPS-collared coyotes are part of a project to learn about how the animals fare in urban settings. So, this coyote is likely one from the Urban Coyote Ecology and Management project, which captures coyotes that make their way into urban areas, fits them with radio collars, and re-releases them in order to study them more closely.

It seems smart at first, though seeing a coyote running down the middle of a road highlights a few problems -- how many of these coyotes become roadkill, or eat up someone's house cat while out prowling for pests? Another issue is brought up in the Chicago Breaking News article: "Earlier this year, another coyote was found in a park near the Chicago River and would return there to scavenge for food, he said. That animal had to be removed because it had become accustomed to people and their handouts. It was eventually taken to a wildlife center."

No one really knows what effect city life has on coyotes -- the project says it best themselves:

Our limited understanding of how coyotes succeed in urban landscapes hampers management of this animal. Even knowledge of their basic ecology is incomplete. This is important because diets, social behavior, movement patterns and survival may change with urbanization. Nevertheless, as coyotes become increasingly abundant in the cities, so does the need for basic information to develop management strategies. In areas where coyotes have existed with people for some time, such as the southwestern United States, conflicts with coyotes threaten the health and well-being of people and pets. Are extreme conflicts the inevitable result of the relatively recent emergence of coyotes in Midwestern and eastern U.S. cities? What are the full ramifications for people, pets, and other wildlife when this remarkable canid suddenly becomes a neighbor?

That's the purpose of the experiment -- to find out how coyotes really fare as urban landscapes take over their natural habitat. Since 2008, the project has captured and collared 250 coyotes. Gathering up information by following the animals will help unveil questions such as how big an impact cities have on coyotes, how it might change their behaviors or food sources, and whether or not they're to be the next raccoon, pigeon, skunk or opossum.

As far as a coyote being released on purpose to eat up rodents...well, that's probably more a tactic to keep city residents calm about their furry neighbors. Instead, the animals-as-pest-control is likely more of a happy side effect of letting the coyotes do their thing in order to find out more about them.

Thursday, July 15, 2010

Artificial Lung "Breathes" in Rats: Study

Reuters: WASHINGTON

http://abcnews.go.com/

U.S. researchers have created a primitive artificial lung that rats used to breathe for several hours and said on Tuesday it may be a step in the development of new organs grown from a patient's own cells.

The finding, reported in the journal Nature Medicine, is the second in a month from researchers seeking ways to regenerate lungs from ordinary cells.

In the latest study, Harald Ott and colleagues at Massachusetts General Hospital and Harvard Medical School in Boston removed the cells from rat lungs to leave a scaffolding or matrix.

They soaked these in a bioreactor along with several types of human lung cells, creating pressures to simulate the pressure inside a body to make the lung workable and flexible.

The cells took up residence and grew into different tissue types seen in a lung, Ott's team reported.

When transplanted into rats, they worked for about six hours, although imperfectly.

The researchers said it may be possible to try the experiment with more immature stem cells, the body's master cells. These could include embryonic stem cells, which can mature into any cell type in the body, or induced pluripotent stem cells -- ordinary cells with genes added to make them behave like flexible stem cells.

The potential market is large and dozens of companies are launching into regenerative medicine, as are academic labs like those at Harvard.

"Nearly 25 million people live with chronic obstructive pulmonary disease and approximately 120,000 patients die from end-stage lung disease annually in the United States alone," Ott's team wrote.

"Lung transplantation remains the only definitive treatment for end-stage lung disease. As with other organs, however, the supply of donor lungs is limited. In 2005, only one out of four patients waiting for a lung underwent transplantation," they added, citing the United Network of Organ Sharing.

Last month, a team at Yale University in Connecticut implanted engineered lung tissue into rats that helped the animals breathe for two hours.

(Editing by Todd Eastham)

Tuesday, March 23, 2010

A sweet problem: Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain

A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.

In addition to causing significant weight gain in lab animals, long-term consumption of high-fructose corn syrup also led to abnormal increases in body fat, especially in the abdomen, and a rise in circulating blood fats called triglycerides. The researchers say the work sheds light on the factors contributing to obesity trends in the United States.

"Some people have claimed that high-fructose corn syrup is no different than other sweeteners when it comes to weight gain and obesity, but our results make it clear that this just isn't true, at least under the conditions of our tests," said psychology professor Bart Hoebel, who specializes in the neuroscience of appetite, weight and sugar addiction. "When rats are drinking high-fructose corn syrup at levels well below those in soda pop, they're becoming obese -- every single one, across the board. Even when rats are fed a high-fat diet, you don't see this; they don't all gain extra weight."

Hoebel lab

A Princeton University research team, including (from left) undergraduate Elyse Powell, psychology professor Bart Hoebel, visiting research associate Nicole Avena and graduate student Miriam Bocarsly, has demonstrated that rats with access to high-fructose corn syrup -- a sweetener found in many popular sodas -- gain significantly more weight than those with access to water sweetened with table sugar, even when they consume the same number of calories. The work may have important implications for understanding obesity trends in the United States. (Photo: Denise Applewhite) Photos for news media

In results published online March 18 by the journal Pharmacology, Biochemistry and Behavior, the researchers from the Department of Psychology and the Princeton Neuroscience Institute reported on two experiments investigating the link between the consumption of high-fructose corn syrup and obesity.

The first study showed that male rats given water sweetened with high-fructose corn syrup in addition to a standard diet of rat chow gained much more weight than male rats that received water sweetened with table sugar, or sucrose, in conjunction with the standard diet. The concentration of sugar in the sucrose solution was the same as is found in some commercial soft drinks, while the high-fructose corn syrup solution was half as concentrated as most sodas.

The second experiment -- the first long-term study of the effects of high-fructose corn syrup consumption on obesity in lab animals -- monitored weight gain, body fat and triglyceride levels in rats with access to high-fructose corn syrup over a period of six months. Compared to animals eating only rat chow, rats on a diet rich in high-fructose corn syrup showed characteristic signs of a dangerous condition known in humans as the metabolic syndrome, including abnormal weight gain, significant increases in circulating triglycerides and augmented fat deposition, especially visceral fat around the belly. Male rats in particular ballooned in size: Animals with access to high-fructose corn syrup gained 48 percent more weight than those eating a normal diet. In humans, this would be equivalent to a 200-pound man gaining 96 pounds.

"These rats aren't just getting fat; they're demonstrating characteristics of obesity, including substantial increases in abdominal fat and circulating triglycerides," said Princeton graduate student Miriam Bocarsly. "In humans, these same characteristics are known risk factors for high blood pressure, coronary artery disease, cancer and diabetes." In addition to Hoebel and Bocarsly, the research team included Princeton undergraduate Elyse Powell and visiting research associate Nicole Avena, who was affiliated with Rockefeller University during the study and is now on the faculty at the University of Florida. The Princeton researchers note that they do not know yet why high-fructose corn syrup fed to rats in their study generated more triglycerides, and more body fat that resulted in obesity.

Hoebel lab

When male rats were given water sweetened with high-fructose corn syrup in addition to a standard diet of rat chow, the animals gained much more weight than male rats that received water sweetened with table sugar, or sucrose, along with the standard diet. The concentration of sugar in the sucrose solution was the same as is found in some commercial soft drinks, while the high-fructose corn syrup solution was half as concentrated as most sodas, including the orange soft drink shown here. (Photo: Denise Applewhite)

High-fructose corn syrup and sucrose are both compounds that contain the simple sugars fructose and glucose, but there at least two clear differences between them. First, sucrose is composed of equal amounts of the two simple sugars -- it is 50 percent fructose and 50 percent glucose -- but the typical high-fructose corn syrup used in this study features a slightly imbalanced ratio, containing 55 percent fructose and 42 percent glucose. Larger sugar molecules called higher saccharides make up the remaining 3 percent of the sweetener. Second, as a result of the manufacturing process for high-fructose corn syrup, the fructose molecules in the sweetener are free and unbound, ready for absorption and utilization. In contrast, every fructose molecule in sucrose that comes from cane sugar or beet sugar is bound to a corresponding glucose molecule and must go through an extra metabolic step before it can be utilized.

This creates a fascinating puzzle. The rats in the Princeton study became obese by drinking high-fructose corn syrup, but not by drinking sucrose. The critical differences in appetite, metabolism and gene expression that underlie this phenomenon are yet to be discovered, but may relate to the fact that excess fructose is being metabolized to produce fat, while glucose is largely being processed for energy or stored as a carbohydrate, called glycogen, in the liver and muscles.

In the 40 years since the introduction of high-fructose corn syrup as a cost-effective sweetener in the American diet, rates of obesity in the U.S. have skyrocketed, according to the Centers for Disease Control and Prevention. In 1970, around 15 percent of the U.S. population met the definition for obesity; today, roughly one-third of the American adults are considered obese, the CDC reported. High-fructose corn syrup is found in a wide range of foods and beverages, including fruit juice, soda, cereal, bread, yogurt, ketchup and mayonnaise. On average, Americans consume 60 pounds of the sweetener per person every year.

"Our findings lend support to the theory that the excessive consumption of high-fructose corn syrup found in many beverages may be an important factor in the obesity epidemic," Avena said.

The new research complements previous work led by Hoebel and Avena demonstrating that sucrose can be addictive, having effects on the brain similar to some drugs of abuse.

In the future, the team intends to explore how the animals respond to the consumption of high-fructose corn syrup in conjunction with a high-fat diet -- the equivalent of a typical fast-food meal containing a hamburger, fries and soda -- and whether excessive high-fructose corn syrup consumption contributes to the diseases associated with obesity. Another step will be to study how fructose affects brain function in the control of appetite.

The research was supported by the U.S. Public Health Service.

Monday, November 24, 2008

Mankind's new best friend? Trained giant rats sniff out land mines, tuberculosis

Bart Weetjens in Tanzania with one of his trained rats. Bart Weetjens in Tanzania with one of his trained rats. (Sylvain Piraux/Apopo International)
By Colin Nickerson Globe Correspondent / November 23, 2008

Reviled as vermin through the ages, rats are becoming unlikely soldiers in the struggle against two scourges of the developing world: land mines and tuberculosis.

In Mozambique, special squads of raccoon-size rats are sniffing out lethal explosive devices buried across the countryside, remnants of the country's anticolonial and civil wars of the last century.

In neighboring Tanzania, teams of rats use their twitchy noses to detect TB bacteria in saliva samples from four clinics serving slum neighborhoods. So far this year, the 25 rats trained for the pilot medical project have identified 300 cases of early-stage TB - infections missed by lab technicians with their microscopes. If not for the rodents, many of these victims would have died and others would have spread the disease.

"It's fair, I think, to call these animals 'hero rats,' " said Bart Weetjens, the Belgian conceiver of both programs.

The rat squads, at first derided by some interna tional aid officials as ridiculous, have won support from the World Bank and praise from the UN and land mine eradication groups. Now there are plans to deploy the creatures to Angola, Congo, Zambia, and other land mine-infested lands.

The rats' "noses are far more sensitive than all current mechanical vapor detectors," Havard Bach, a mine-clearing specialist with the Geneva International Center for Humanitarian Demining, wrote in a study.

Although rats make almost everyone's short list of horrors - associated with filth, disease, and destruction of food crops - they "are really nice creatures," according to Weetjens.

"They are organized, sensitive, sociable, and smart," said the former product engineer in a telephone interview from Antwerp, Belgium, home base for Apopo International, the nonprofit organization that trains and deploys the rats.

In the 1990s, he journeyed to Africa to study land mine clearance techniques. He put his engineer's mind to the expensive, clumsy, and often risky methods employed to detect the lethal contraptions of metal and explosive that detonate underfoot.

Land mines claim casualties for decades after the last shot is fired in a conflict; millions are strewn in former and present fighting zones across Africa, Asia, and Europe. The wickedly durable antipersonnel devices kill or maim thousands of people every year, mainly in the poorest of countries. Removal of the weapons is a priority of the United Nations and other groups.

"In Africa, it came to me: Rats can be part of this great effort," Weetjens recalled.

So he started training giant pouched rats - an African species known for its large size, sunny disposition, and ultra-keen nostrils - to detect the faintest whiff of TNT and other explosives. Because the rats are too light to trigger the explosive, they are not harmed in the exercise; they simply signal the location of the explosive to a handler, who has it defused and removed.

The rat land mine-clearing program in Mozambique, although still small in scale, has been operational for two years - with 34 trained rats deployed to the field, each overseen by a pair of armor-clad handlers. Another 250 mine-detecting rats are undergoing schooling at Tanzania's Sokoine University of Agriculture. It takes 8 to 10 months to fully train a rat, said Weetjens.

A single rat can inspect 1,000 square feet in about 30 minutes, according to Apopo; that's at least a full day's labor for a human working with an electronic detector at terrible risk.

Rat teams are credited with clearing 270 square miles of former farm and village land in southern Mozambique, allowing for the return of peasant families dislocated since the 1980s.

Dogs can perform the same task. But rats are less expensive to train ($3,000 to $5,000 per animal, compared with $40,000 for a canine), easier to house and transport, and far less susceptible to tropical disease. Also, dogs can trip land mines.

Also, rats don't form deep emotional attachments to a single handler. A rat will happily work with anyone who gives the right commands and provides the correct payoff - a few peanuts or a nice ripe banana for locating a land mine, said Andrew Sully, Mozambique program manager for Apopo.

The rodents are hitched to a light leash and scamper in tight grid patterns in suspected land mine sites. When they scent explosive, they signal with furious digging motions. They typically work from 5 to 9 a.m., quitting when the ferocious African sun gets too hot.

"People are so surprised to see this" project, said Alberto Jorge Chambe, a Mozambican rat handler for Apopo. "Rats are usually considered pests or enemies of humanity. But rats are helping my country escape the shadow of death."

Meanwhile, in a conceptual leap, Weetjens decided to turn the rats' sharp olfactory sense to disease detection, starting with tuberculosis. "The medical applications, I believe, will eventually prove even more important than the hunt for land mines," he predicted.

In the pilot project in the Tanzanian capital of Dar es Salaam and the nearby city of Morogoro, Apopo-trained rats evaluate saliva samples at a rate of 40 every 10 minutes; that's equal to what a skilled lab technician, using a microscope, can effectively complete in a day.

A TB rat signals with unmistakable paw motions when it detects sputum infected by Mycobacterium tuberculosis, the infectious bug responsible for 1.7 million deaths and 9.2 million new TB cases each year, mainly in poor countries, according to the World Health Organization. Scientists at Germany's Max Planck Institute are now trying to determine whether the rats are detecting the scent of the actual TB bacteria or some metabolic reaction produced by the infection.

For both TB and land mines, the rats are trained to respond to the sound of a clicker; when the rat makes the scratching motion that means it has detected an explosive or the odor of disease, the handler or trainer responds by snapping the clicker, which means a nut or fruit is on the way.

So why don't the animals just scratch every few minutes to win a treat?

"That would be human behavior," said Weetjens. "Rats are more honest."

Colin Nickerson can be reached at nickerson.colin@gmail.com.

Monday, October 20, 2008

The incredible surfing rats who were taught to ride 4ft waves

By Daily Mail Reporter

He looks like a drowned rat. But clinging to his very own surfboard, this is simply a pet exploring his wild side.

Tofu, as he is known, and his 14-year-old owner hit the waves twice a week at their local beach in Hawaii.

Along with his fellow rat Fin, Tofu catches waves of up to 4ft and even rides tunnels of water known as 'tubes'.

Enlarge surf

Surfin' USA: Boomer Hodel with Tofu his incredible surfing rat. The teenager built a surfboard for his rats Tofu and Fin and spent weeks teaching them to hold on until they can now handle full tube waves in Haleiwa, Hawaii

'Running on a wheel isn't enough for Fin and Tofu - they like a more extreme rush,' said owner Boomer Hodel.

'When they first started they were pretty shaky and would fall off quite a lot, but now their balance is so good they fall off less than most human surfers.'

The rats - both one-year-olds - surf for 20 minutes at a time before drying off in the sun.

Each time, they are raring to get back to the water. 'Rats are natural swimmers,' Boomer said. 'And they have a very adventurous spirit.'

Hodel started their training by gently pushing the rats into tiny ripples at the water's edge before moving them on to more advanced waves.

Both the rats can swim and, after some early tumbles, can now perform tricks - often catching tubes in front of stunned onlookers.

Hodel draws big crowds of spectators at his local Laniakea Beach.

rat

Both the rats can swim and after some early tumbles can now perform tricks

He said: 'They love surfing. Fin's favourite trick is a tube ride - where the wave breaks over him and he rides through a tunnel of water.

'Sometimes he falls off his board and I have to take him back to the beach to warm him up with a towel. But he is always raring to get back out there.

'The first time I took the rats down to the beach it was to give them a wash because they were all dirty. But they loved the water so much I had to take them back.'

Enlarge rat

Hang 10: Hodel started by gently pushing the rats into tiny ripples at the water's edge, then moved on to more advanced waves and taught him to perform tricks like 'tube-riding'

The water-loving rats are even on a special diet to stay in shape.

'It has really boosted their performance,' said Hodel.

'I give them high protein, low carbohydrate foods. Rats are natural swimmers and have a very adventurous spirit.'

He made the 1ft-long surfboards himself with the help of pals Jeremy Martin and Akila Barrnett , both 14.

ratical

Ratical: Children watch Fin the incredible surfing rat in action

Hodel got the idea when he snapped his surfboard on a big wave and decided to turn each half into a smaller surfboard using sandpaper and fibreglass.

His incredible pets were caught on camera by Hawaiian photographer Clark Little.

He said: 'I saw these kids walking down the beach with two rats and some tiny surfboards so I went over to see what they were doing.

'I couldn't believe it when the rats started surfing. They was really good, surfing very fast and having a grand old time.

'I thought it was weird at first at first but they both seem to really enjoy it and the rats are good swimmers.

'Rats are survivors. Maybe that's why these ones are so good at extreme sports.'

Enlarge hodel

Wipe-out: Hodel takes his pets surfing for 20 minutes at a time before heading back to the beach to warm up in the sun and dry off with a towel