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Saturday, April 5, 2008

Top 5 Recreational Drug Experiments

By Aaron Rowe EmailApril 05, 2008 | 11:46:38 AM

Facemask Recreational drugs are a ridiculously fun topic for scientific research. They could also be the inspiration for powerful new medications. We are often amazed by the fascinating, and sometimes hilarious, stories that make their way into peer-reviewed journals. Here are some of our very favorites:

5. Harvard Scientists Build a Device to Smoke Weed During a Brain Scan
To better understand addiction, and how to treat it, scientists need to get a better look at the human brain as it is under the influence of weed. Unfortunately, smoking weed inside the narrow chamber of a functional MRI is not easy. To prevent smoke damage and allow their research subjects to puff without moving around too much, Blaise Frederick and his team at Harvard built what amounts to a giant bong.

4. Stanford Chemists make THC from Scratch
Since 1965, chemists have been trying to make the active ingredient of marijuana [pdf]from scratch. Back then, the researchers could only make tetrahydrocannabinol along with its enantiomers -- impurities that have the same chemical composition, but a different shape. Then, in 2006, a pair of chemists from Stanford University used a Molybdenum catalyst and other sophisticated techniques to produce the coveted molecule in its pure form. Despite their discovery, mother nature is still the best chemist and closets with high-intensity lamps will outperform the most sophisticated laboratories.

3. Researchers Learn How Salvia Works
Diviner's sage contains a powerful hallucinogen that may someday inspire a new class of depression, pain, and addiction medications. In at least one instance, a woman has used the substance to rid herself of depression. Tests on animals have shown that the Oxaccan plant, a relative of the culinary herb, can also control pain.

Last year, Catherine Willmore and her colleagues at Ohio Northern University ended a controversy about how the drug works. In the Sep. 2007 issue of Neruopharmacology, she explained that the active chemical, Salvinorin A, binds to signal-carrying proteins called kappa opioid receptors.

Willmore and her team trained rats to recognize the sensations caused by a well-understood drug that also targets kappa opioid receptors. It is impossible to know exactly how the rats felt during the test, but they could not tell the difference between the active chemical in sage and the one they had been trained to identify. Since the drugs feel the same, both of them must activate the same target.

2. British Army Tests LSD on Soldiers

1. Researchers Combine Chemicals from Sea Urchin Eggs and Weed to Make Powerful Painkillers
Scientists at organix, a small research and development firm, made hybrid molecules which resemble the euphoria-causing compounds THC and anandamide. In the Dec. 2007 issue of Bioorganic and Medicinal Chemistry they explained that both drugs have their own unique advantages and disadvantages. Anandamide starts working faster than its marijuana-derived counterpart, but it is more quickly destroyed by the body. A fusion of the two chemicals may last longer while maintaining an equal or stronger effect.

Although the researchers at Organix did not comment on the recreational potential of their new chemicals, their data makes it very clear that the new drugs push the same pleasure buttons as THC and anandamide.

Image Credit: Blaise Frederick / Harvard

Learn How To Hijack A Drive Thru Frequency

How To Hijack A Drive Thru

Posted 3/20/2008
Runtime: 9:11

Dudes explain how you too can prank your local fast food joint's drive thru.

How Hallucinogens Play Their Mind-Bending Games

Researchers isolate cells affected by LSD & Mescaline, potentially leading to more treatments for neurological and psychiatric disorders.

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Rich Boys Toys - Cobra Helicopter

If you have the money you too could own one of these..

Charles Manson Releases Record Under Creative Commons

charlesmanson.jpgCelebrity endorsements aren't always a good thing. Take, for example, Lawrence Lessing's opensource copyright organization, Creative Commons. Sure everyone was excited when Trent Reznor moved a trillion copies of the new Nine Inch Nails record using the license, but the same doesn't seem to apply to Charles Manson.

Perhaps it's the whole brainwashing/cult/murder thing that trips people up. But people seem to forget that before Chuck was carving swastikas into his forehead, he was keeping himself busy as an struggling songwriter--even managing at one point to land a composition on a Beach Boys album.

Thanks in part to an abundance of spare time, Manson has managed to record another record, this time out bearing the typically ominous title, One Mind. The album is licensed under Creative Commons, meaning that anyone can share and remix the thing for non-commercial purposes.

The full record is available for free download via Limewire for the morbidly curious.

52 Girls Removed From Secretive Ranch of Polygamist Leader

Nearly 200 Taken From Texas Compound

Nearly 200 Now Removed From Polygamist Compound Where Officials Sought 50-Year-Old, Teen Wife


The Associated Press

Officials escort two buses Friday April 4, 2008 from the retreat built by the Fundamentalist Church of Jesus Christ of Latter Day Saints,...


Child welfare officials have now removed nearly 200 women and children from a secretive West Texas religious retreat built by polygamist leader Warren Jeffs, authorities said Saturday.

The investigation began after a 16-year-old living there complained of physical abuse. A search warrant authorized state troopers to enter the retreat run by the Fundamentalist Church of Jesus Christ of Latter Day Saints and look for evidence of a marriage between the girl and a 50-year-old man.

The warrant said the girl had a baby eight months ago, when she was 15.

State Child Protective Services on Friday removed 52 girls from the compound. Marleigh Meisner, a spokeswoman for the agency, said that another 131 residents were removed overnight and that by Saturday afternoon 137 children and 46 women were being housed and interviewed.

"They seem to be doing fine," Meisner said. Four investigators remained inside the polygamist compound looking for additional children.

The whereabouts of the young mother who sparked the investigation are unknown, Meisner said.

State troopers who raided the religious retreat were looking for the girl, her baby girl and 50-year-old Dale Barlow. Under Texas law, girls younger than 16 cannot marry, even with parental approval.

Barlow had not been found by Friday night, officials said then. They declined to comment Saturday, saying a state judge had issued a gag order.

The search warrant instructed officers to look for marriage records or other evidence linking the girl to Barlow and the baby. The warrant authorized the seizure of computer drives, CDs, DVDs or photos.

Those inside the retreat did not respond to requests for comment.

The Fundamentalist Church of Jesus Christ of Latter Day Saints broke away from the Mormon church after the latter disavowed polygamy more than a century ago.

State law enforcers declined to comment Saturday, saying a judge had issued a gag order, and the local sheriff did not return calls.

The Fundamentalist Church of Jesus Christ of Latter Day Saints broke away from the Mormon church after the latter disavowed polygamy more than a century ago.

The compound sits down a narrow paved road and behind a hill that shields it almost entirely from view in town. Only the 80-foot-high gleaming white temple can be seen on the horizon. Authorities blocked access to the gate, keeping onlookers miles away.

The 1,700-acre property had been an exotic game ranch. It is surrounded by dusty, wind-swept land where sheep are raised and mohair produced.

Eldorado (pronounced el-dor-AY'-do) is a two-stoplight town of fewer than 2,000 people nearly 200 miles northwest of San Antonio. It consists of a cluster of government buildings, a couple of churches and a few blocks of houses.

State officials said they did not know how many people lived at the retreat, although local officials estimated about 150 two years ago.

The group, known by the acronym FLDS, has been led by Jeffs since his father died in 2002. In November, Jeffs was sentenced to two consecutive sentences of five years to life in prison in Utah for being an accomplice to the rape of a 14-year-old girl who wed her cousin in an arranged marriage in 2001.

In Arizona, Jeffs is charged as an accomplice with four counts each of incest and sexual conduct with a minor stemming from two arranged marriages between teenage girls and their older male relatives. He is jailed in Kingman, Ariz., awaiting trial.

The San Angelo Standard-Times reported that children were being kept at a community center and a Baptist church in Eldorado.

The owner of the Sutton County Steak House in nearby Sonora fed the children dinner on Friday and breakfast on Saturday, owner Linda Love told The San Angelo Standard-Times.

"They're singing songs. So happy and sweet and precious. It's heart-breaking," Love said.

The Ultimate Hotel Room Finder!

A Google Maps mashup called the Map Channels Hotels Directory shows you all hotels with availability listed in order of price. Just punch in the city, the check-in date and the number of nights you'll be staying, and it will lay out all your options. (Stay in New York City for $16 per night! Wow!)

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How to find and get free WIFI access ?

WIFIWi-Fi a short name for Wireless Fidelity, is the popularly used wireless technology to connect to Internet in homes, colleges, hotels, Airports, coffee shops etc. To read more about how wifi works, read here. People who travel a lot often find it very difficult to locate and access the wireless access points or hot spots in the cities where they stay or travel. There are few free tools and web applications available in the internet to solve this problem and you can locate and access the WIFI hot spots around your place with ease.


JiWireJiWire is a leading Wi-Fi advertising network, delivering premium, location-driven Ads for Access at premier Wi-Fi locations. You can use JiWire service online as a web application and performing a web search or you can find the hot spot near you place by using JiWire Hotspot Bot for skype. JiWire is a hotspot finder which has a database of more than 2 lakh hotspots in more than 135 countries. Using JiWire one can find both free and paid hotspots. Using JiWire you can locate yourselves in the map and also you can find the free and paid hot spots around you.

JiWire Chat Bot

JiWire is able to locate you based on your IP address and may not be accurate at time but still it works good with major cities of the world. Also Jiwire helps you to register a hotspot by a single click if you find one and also it provides some free wifi tools to test your wifi security too. The installation and usage of JiWire is so easy. After installing just open the Skype BOT from the menu and start using the tool. You can download the JiWire skype bot here.

Easy Wifi Radar

Easy Wifi Radar Scanning

You can use Easy WiFi Radar to find and connect to open wireless access points around you with a single mouse click. It’s really just WiFi for Dummies. If you feel very lazy to to scan, search and connect to a open Wifi Access then you can use this tool. Easy Wifi Radar scans the network around you and look for open WIFI hot spots and automatically connects to it and then opens a web page automatically to check the connection. To see a demo about Easy Wifi Radar please see the Youtube video below,

Digg users unite!!! Let's Rickroll the NY Mets all year!!!

choose other on the ballot, write in the entry, and all year the Mets and their fans get rickrolled during the 8th inning. DO IT!!!Click Other: then type Never Gonna Give You Up - Rick AstleyThis is chance to see the power of the Internet, the power of DIGG, and of course the chance to RickRoll entire City!!!!

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Perfectly Timed Pictures

Some of these are repeats, but they are so Perfect!!! I love the age of Digital Photography